Anabolic resistance increases with age, meaning your muscles require a larger protein stimulus to achieve the same preservation response
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Its also important to note that for patients using Wegovy to reduce heart attack and stroke risk, which Australias Therapeutic Goods Administration recently approved it for, theres no evidence that cardiovascular benefits will be achieved at lower-than-recommended doses
With careful dose titration and timing to align with meals, the risk of insulin oversupply and hypoglycaemia can be minimised, and several glucokinase activators with variable effects on beta cells vs liver have improved glycaemic control in clinical studies [21]
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